ncRNA name | Hottip |
ncRNA Category | lncRNA |
ID | NA |
Ensembl | NA |
Synonyms | NA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | shRNA knockdown, qRT-PCR, Western blot |
Expression pattern | up-regulated |
Functional description | HOTTIP improves diabetic retinal microangiopathy through the p38-MAPK pathway. Down-regulation of HOTTIP can reduce the visual function decline and apoptosis of retinal cells caused by diabetes. |
PubMed ID | 29863235 |
Year | 2018 |
Title | LncRNA HOTTIP improves diabetic retinopathy by regulating the p38-MAPK pathway. |
Drug-related ncRNA | NO |
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